Statement of Specific Principles for Clinical Evaluation of Drugs/Vaccines/Devices/Diagnostics/Herbal Remedies etc.
The recent developments in frontier areas like genome mapping, genetic recombinant engineering, assisted reproductive biology, stem cell research, have opened up hither to unknown practical applications of these technologies. However, these exciting areas also raise some delicate and sensitive issues regarding ethics in Bio-medical research. Accordingly, as a sequel to the “Policy Statement on Ethical […]
Sleep Disorders
Millions of Indians are plagued by Sleep Disorders. It is a serious public health risk that too many doctors ignore. Half of Sleep Disorders consist of lack of sleep while other half consist of daytime sleepiness or over sleep. Sleep for certain hours is a compulsory physiological event of the brain for proper functioning of […]
Sex and Drug Effect
Sex and effect of drugs is an important topic since many drugs that are prescribed for common conditions such as anxiety and hypertension interfere with sexual functioning. Two cases are illustrated here. CASE I 30 years old Mr. S K was married for two years. he had no premarital contact. He was childless since he advised […]
Scope and Practice of Industrial Hygiene and its Relevance to Occupational and Environmental Health
A hazard is anything with the potential of producing an adverse outcome and is omnipresent in industries. The hazards may be chemical (dust, fibers, vapors, fumes, gas etc.), physical (noise, temperature, radiation etc.), biological (bacteria, fungi, viruses etc.) ergonomic and psychosocial. Unfortunately, a hazard is not identified until an accident or adverse incident occurs. Proactive […]
Safety in Use of Chemicals
In India, the Bhopal Gas Tragedy had triggered awareness on chemical risk and safety associated with industries. Many chemical safety guidelines have been adopted since this accident, but still in a large number of industries this issue remains at the lowest rung of priority. Almost all the chemicals used in industries have the potential of […]
Practical Pearls on Glaucoma
Never diagnose Glaucoma on the basis of a single high reading of Intraocular Pressure (IOP). Remember one swallow doesn’t make a summer! To diagnose glaucoma, all three tests viz. IOP, Perimetry (by a good standard perimeter), and Fundoscopy should be done. Two consecutive positive tests on two separate occasions should clinch the diagnosis not otherwise. Patient […]
Position Measurement of Endotracheal Tube during Ventilation
To study available and modern techniques for position measurement of endotracheal tubes. The need for Instrumentation is to make proper and accurate measurement of various parameters related to medical science. All measurement mainly depends on the detection, acquisition and display of biological signal. Respiration is to get Oxygen into the body and Waste Gases out […]
Osteoarthritis: Current concepts
What Is Osteoarthritis? Also known as degenerative joint disease or osteoarthrosis, osteoarthritis is a joint disease that affects cartilage, the tissue that covers the ends of bones in a joint. Healthy cartilage allows bones to glide over one another, absorbing the shock of sudden physical movements. When a person has osteoarthritis, cartilage breaks down and […]
Neurodegenerative Disorders and Oxidative Stress
Studies using experimental models and human brain have demonstrated the possible role of oxidative stress in neuronal degenerative disorders like, epilepsy, stroke, Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease, and amyotrophic lateral sclerosis by causing damage in cell membrane, lipid peroxidation, protein oxidation and carbohydrate damage and DNA damage which ultimately leads to either necrotic or […]
MN & CA: Biomarkers for Genotoxicity
Across the Globe, it is known from ancient time, mineral fibres having great deal of importance for its use in the manufacturing of different kind of mineral based-products. Asbestos is one of the fibrous mineral silicates, which accounts more than 3,000 of its uses all over the World (Ramanathan and Subramanian, 2001). In India, there […]
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